TOC analytical method in cleaning validations: criteria, limits and robustness of the process
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| Models | Chlorine and Sulfur Analyzer / Total Organic Halogen Analyzer model TOX-300 |
| Method of analysis | Oxidative decomposition / Columbimetric titration |
| Oxidative decomposition | Quartz tube combustion method |
| Samples | Liquid, solid and gaseous (using gas injector model GI-210) |
| Sample introduction | Automatic sample introduction with a small vessel (ABC-210 unit) |
| Pyrolytic oven | Horizontal oven: up to 1.100 ⁰C |
| Detection method | Oxidation-reduction potential (potentiometric detection by potential) |
| Detector electrode | Chlorine measurement: silver electrode Sulfur measurement: platinum electrode |
| Valuation control | Automatic control of electrolytic current |
| Measurement ranges | See Table of measuring ranges |
Measurement ranges:
| Absolute volume | Solid samples | Liquid samples | Gaseous samples |
| Chlorine: 0.05 µg/ml to 50 µg | 2 µg/g (30mg) | 0.5 µg/ml (100 µl) | 5mg/m3 (10ml) |
| Sulfur: 0.05 µg/ml to 50 µg | 2 µg/g (30mg) | 0.5 µg/ml (100 µl) | 5mg/m3 (10ml) |
| Sample volume | liquid samples: less than 100 µl, solid samples: less than 30 mg |
| Analysis time | Less than 10 min/measurement (2µg measurements) |
| Temperature and humidity | 15 to 35 ⁰C, below 80 % RH (Non-condensing) |
| Dimensions | TOX-300 main unit: 550 x 360 x 437 mm (W x D x H)
ABC-210: 440 x 250 x 180 mm ( W x D x H ) |
| Weight | TOX-300 main unit: 36 Kg ABC-210: 11 Kg |
| Computer / O.S. | Windows® 7 Preinstalled version English |
| Printer | Windows® compatible printer |
| Gas | Oxygen (purity greater than 99.7%) Argon (purity greater than 99.98 %) |
| Power supply | TOX-300 main unit: AC 100 to 240 V, 50/60 Hz, 980 VA ABC-210: AC 100 to 240V, 50/60 Hz, 40 VA |
AOF – PFAS
AOX – Adsorbable Organic Halogens
EOX – Extractable Organic Halogens
ISO 9562
ASTM D5808
ASTM D3120
ASTM D3246
ASTM D3961
EPA 9020B
EPA 9021
EPA 9076
ISO 11480
DIN 38414-17
DIN 38414- 18
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Pide información de Halogen and Sulfur Analyzer Model TOX-300
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