TOC analytical method in cleaning validations: criteria, limits and robustness of the process
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Meticulous quality control throughout the entire production process is a must in all areas of industry. Especially in the pharmaceutical, chemical, petrochemical, food and beverage industries, densimetry is frequently used, which allows the analysis of a multitude of factors of raw materials, intermediate and final products as well as stages of the manufacturing process. From density it is possible to identify substances, to determine their quality or purity and to measure their concentration in binary or quasi-binary mixtures. Furthermore, substance transformations and reaction dynamics can be analyzed.
In this article we discuss laboratory density meters, how density measurement of liquids works, what is digital density measurement based on the U-tube principle, applications, standards, sample types and automation in density measurement with density meters from A. Krüss Optronic GmbH.
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